{"id":1168,"date":"2022-08-08T07:19:34","date_gmt":"2022-08-08T07:19:34","guid":{"rendered":"http:\/\/raastriple-a.com\/?page_id=1168"},"modified":"2023-05-19T13:03:47","modified_gmt":"2023-05-19T13:03:47","slug":"doctors","status":"publish","type":"page","link":"https:\/\/raastriple-a.com\/de\/doctors\/","title":{"rendered":"Doctors"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"1168\" class=\"elementor elementor-1168\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e8f792a elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"e8f792a\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-35b9896\" data-id=\"35b9896\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-422b5bf e-transform elementor-widget elementor-widget-image\" data-id=\"422b5bf\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.094,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.031,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.12.1 - 02-04-2023 *\/\n.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=\".svg\"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"474\" src=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/08\/doctor_banner-1024x474.png\" class=\"attachment-large size-large wp-image-1173\" alt=\"\" srcset=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/08\/doctor_banner-980x454.png 980w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/08\/doctor_banner-480x222.png 480w\" sizes=\"auto, (min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1024px, 100vw\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-58df6a87 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"58df6a87\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2693fa92\" data-id=\"2693fa92\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b4647ef e-transform e-transform elementor-widget elementor-widget-heading\" data-id=\"b4647ef\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:0.4,&quot;sizes&quot;:[]},&quot;_transform_translateX_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:14,&quot;sizes&quot;:[]},&quot;_transform_translateX_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:94,&quot;sizes&quot;:[]},&quot;_transform_translateY_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:-104,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:0.7,&quot;sizes&quot;:[]},&quot;_transform_translateX_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_translateY_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_translateY_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.12.1 - 02-04-2023 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h2 class=\"elementor-heading-title elementor-size-default\"><h1 style=\"text-align: left;\"><span style=\"color: #004874;\">A unique lab test for <\/span><\/h1>\n<h1 style=\"text-align: left;\"><span style=\"color: #004874;\">hypertension profiling<\/span><\/h1><\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3576802 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"3576802\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-34bcce5\" data-id=\"34bcce5\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-66d990c elementor-widget elementor-widget-heading\" data-id=\"66d990c\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\"><p style=\"text-align: center;\"><span style=\"font-family: var( --e-global-typography-primary-font-family ), Sans-serif; font-size: 26px; font-weight: var( --e-global-typography-primary-font-weight );\"><font color=\"#ffffff\">Hypertension as the main risk for cardiovascular events<\/font><\/span><span style=\"font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-size: 22px; font-weight: var( --e-global-typography-text-font-weight );\"><\/span><\/p><\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-44d0892 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"44d0892\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-top-column elementor-element elementor-element-f85e789\" data-id=\"f85e789\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ac80cc2 e-transform elementor-widget elementor-widget-text-editor\" data-id=\"ac80cc2\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_translateX_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:0,&quot;sizes&quot;:[]},&quot;_transform_translateY_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:24,&quot;sizes&quot;:[]},&quot;_transform_translateX_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_translateX_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_translateY_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_translateY_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.12.1 - 02-04-2023 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p>Uncontrolled hypertension affects more than 50% of patients treated for their high blood pressure. Underlying causes are manifold and it is therefore challenging to identify the cause of inefficient blood pressure lowering therapy in clinical practice. Diagnostic tools that have been available so far to screen for frequent forms of secondary hypertension, like primary aldosteronism, suffer from interference with anti-hypertensive therapies and require drug withdrawal before screening, leading to very low screening rates. However, more than every 10th high blood pressure patient is affected by primary aldosteronism. General practitioners frequently have to go the trial and error path when seeking to control hypertension in their patients.\u00a0Without knowing the underlying molecular causes, this might result in frustration among patients, inappropriate drug prescriptions and also increases in the overall cardiovascular risk due to a long time to blood pressure control.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-35edf2c\" data-id=\"35edf2c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4d57b00 e-transform e-transform elementor-widget elementor-widget-image\" data-id=\"4d57b00\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_translateX_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:-10,&quot;sizes&quot;:[]},&quot;_transform_translateY_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:-16,&quot;sizes&quot;:[]},&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.1,&quot;sizes&quot;:[]},&quot;_transform_translateX_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:0,&quot;sizes&quot;:[]},&quot;_transform_translateY_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.2,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1,&quot;sizes&quot;:[]},&quot;_transform_translateX_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_translateY_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"335\" height=\"411\" src=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/hypertonie.png\" class=\"attachment-large size-large wp-image-2961\" alt=\"\" srcset=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/hypertonie.png 335w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/hypertonie-245x300.png 245w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/hypertonie-10x12.png 10w\" sizes=\"auto, (max-width: 335px) 100vw, 335px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-bf21654 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"bf21654\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-b749e0c\" data-id=\"b749e0c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2717d45 elementor-widget elementor-widget-heading\" data-id=\"2717d45\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\"><p style=\"text-align: center;\"><span style=\"font-family: var( --e-global-typography-primary-font-family ), Sans-serif; font-size: 26px; font-weight: var( --e-global-typography-primary-font-weight );\"><font color=\"#ffffff\">What is RAAS Triple-A\u2122 analysis?<\/font><\/span><span style=\"font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-size: 22px; font-weight: var( --e-global-typography-text-font-weight );\"><\/span><\/p><\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c5471d8 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"c5471d8\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-top-column elementor-element elementor-element-c2c34af\" data-id=\"c2c34af\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-39f967c elementor-widget elementor-widget-image\" data-id=\"39f967c\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"597\" height=\"505\" src=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/angiotensin_diagram.png\" class=\"attachment-large size-large wp-image-3064\" alt=\"\" srcset=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/angiotensin_diagram.png 597w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/angiotensin_diagram-480x406.png 480w\" sizes=\"auto, (min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) 597px, 100vw\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-4ae8e89\" data-id=\"4ae8e89\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-bbe4989 e-transform elementor-widget elementor-widget-text-editor\" data-id=\"bbe4989\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_translateX_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:0,&quot;sizes&quot;:[]},&quot;_transform_translateY_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:39,&quot;sizes&quot;:[]},&quot;_transform_translateX_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_translateX_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_translateY_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_translateY_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>The Renin-Angiotensin-Aldosterone-System (RAAS) is critically involved in the regulation of fluid balance and blood pressure. It serves as a major target for the pharmacologic treatment of hypertension. The RAAS Triple-A\u2122 hormones (Angiotensin I, Angiotensin II and Aldosterone) and their receptors represent key molecular players in mediating physiologic hormonal effects.<\/p><p><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Up until now, the laboratory evaluation of the RAAS has been primarily based on measuring Renin, which is the upstream precursor of Angiotensin II, the actual effector hormone of the RAAS. Recent doubts related to the reliability of such methods led to a surge in clinical LC-MS\/MS for Aldosterone, while an LC-MS\/MS based method for the simultaneous measurement of Renin is still not available yet.<\/span><\/p><p>For the first time, RAAS-Triple-<span style=\"font-size: 14px; background-color: #ffffff;\">A\u2122<\/span>\u00a0analysis, and subsequent calculation of Angiotensin-based biomarkers paved the way for the simultaneous LC-MS\/MS based assessment of Aldosterone concentration, renin activity and ACE activity in standard serum samples. This allows for an in-depth assessment of RAAS dynamics, which includes screening for secondary hypertension (primary aldosteronism, PA) using the Aldosterone-to-Angiotensin II ratio (AA2-R).<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7abc7c9 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"7abc7c9\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d49090c\" data-id=\"d49090c\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-cc92d78 elementor-widget elementor-widget-heading\" data-id=\"cc92d78\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\"><p style=\"text-align: center;\"><span style=\"font-family: var( --e-global-typography-primary-font-family ), Sans-serif; font-size: 26px; font-weight: var( --e-global-typography-primary-font-weight );\"><font color=\"#ffffff\">Angiotensin-based biomarkers<\/font><\/span><span style=\"font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-size: 22px; font-weight: var( --e-global-typography-text-font-weight );\"><\/span><\/p><\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-67ba414 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"67ba414\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-779651a\" data-id=\"779651a\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ba195f8 e-transform elementor-widget elementor-widget-image\" data-id=\"ba195f8\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.2,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"250\" height=\"180\" src=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/PRA_S.png\" class=\"attachment-large size-large wp-image-3012\" alt=\"\" srcset=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/PRA_S.png 250w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/PRA_S-18x12.png 18w\" sizes=\"auto, (max-width: 250px) 100vw, 250px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-31aa7e4\" data-id=\"31aa7e4\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-435abe2 e-transform elementor-widget elementor-widget-image\" data-id=\"435abe2\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.2,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"250\" height=\"180\" src=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/ACE_S.png\" class=\"attachment-large size-large wp-image-3013\" alt=\"\" srcset=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/ACE_S.png 250w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/ACE_S-18x12.png 18w\" sizes=\"auto, (max-width: 250px) 100vw, 250px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-43d4d20\" data-id=\"43d4d20\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-68d0a5b e-transform elementor-widget elementor-widget-image\" data-id=\"68d0a5b\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.2,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"250\" height=\"180\" src=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/AA2_Ratio.png\" class=\"attachment-large size-large wp-image-3014\" alt=\"\" srcset=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/AA2_Ratio.png 250w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/AA2_Ratio-18x12.png 18w\" sizes=\"auto, (max-width: 250px) 100vw, 250px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ecf43f2 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"ecf43f2\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-1693d0f\" data-id=\"1693d0f\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-64c9d18 elementor-widget elementor-widget-text-editor\" data-id=\"64c9d18\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>PRA-S:<\/strong>\u00a0Angiotensin based marker for renin, the pacemaker enzyme of the Renin-Angiotensin-Aldosterone system (RAAS).\u00a0<\/p><p><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Renin is secreted by the kidney and is regulated by renal hemodynamics, fluid and salt balance as well as Angiotensin II itself.\u00a0<\/span><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Most antihypertensive drugs have direct or indirect effects on Renin secretion.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-195fadc\" data-id=\"195fadc\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-384004e elementor-widget elementor-widget-text-editor\" data-id=\"384004e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>ACE-S:<\/strong>\u00a0Angiotensin based marker for the activity of Angiotensin converting enzyme (ACE), which is the main vascular and systemic producer of Angiotensin II. ACE-S is obtained by calculating the ratio between Angiotensin II and Angiotensin I.\u00a0<span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">ACE-S in a patient sample is a measure for the pharmacologic efficacy of an ongoing ACE inhibitor therapy.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-e0ab49d\" data-id=\"e0ab49d\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1bfc1c3 elementor-widget elementor-widget-text-editor\" data-id=\"1bfc1c3\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>AA2-Ratio:<\/strong>\u00a0The ratio of Aldosterone to Angiotensin II reflects the responsiveness of adrenal glands for Angiotensin II. In primary aldosteronism, which affects up to 10 % of hypertensive patients, this ratio is increased because excess Aldosterone secretion is largely independent of Angiotensin II. In patients with essential hypertension treated with ARBs, the AA2-Ratio is suppressed and can be used to monitor drug efficacy<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ce2a601 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"ce2a601\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3fa9cd7\" data-id=\"3fa9cd7\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b3d2008 elementor-widget elementor-widget-heading\" data-id=\"b3d2008\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\"><p style=\"text-align: center;\"><span style=\"font-family: var( --e-global-typography-primary-font-family ), Sans-serif; font-size: 26px; font-weight: var( --e-global-typography-primary-font-weight );\"><font color=\"#ffffff\">RAAS Triple-A\u2122 Kit<\/font><\/span><span style=\"font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-size: 22px; font-weight: var( --e-global-typography-text-font-weight );\"><\/span><\/p><\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2455e3d elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"2455e3d\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-top-column elementor-element elementor-element-61d8ed1\" data-id=\"61d8ed1\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d1d5010 e-transform e-transform elementor-widget elementor-widget-image\" data-id=\"d1d5010\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_translateX_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:3,&quot;sizes&quot;:[]},&quot;_transform_translateX_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:0,&quot;sizes&quot;:[]},&quot;_transform_translateY_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:45,&quot;sizes&quot;:[]},&quot;_transform_translateY_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:23,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.2,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1,&quot;sizes&quot;:[]},&quot;_transform_translateX_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_translateY_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"576\" height=\"475\" src=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/tubebox_v2_gray130722.png\" class=\"attachment-large size-large wp-image-235\" alt=\"\" srcset=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/tubebox_v2_gray130722.png 576w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/tubebox_v2_gray130722-480x396.png 480w\" sizes=\"auto, (min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) 576px, 100vw\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-beb1b2d\" data-id=\"beb1b2d\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b07a49e e-transform elementor-widget elementor-widget-text-editor\" data-id=\"b07a49e\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_translateX_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:0,&quot;sizes&quot;:[]},&quot;_transform_translateY_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:35,&quot;sizes&quot;:[]},&quot;_transform_translateX_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_translateX_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_translateY_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_translateY_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>The RAAS Triple-A\u2122 kit (CE-IVD) is a powerful routine laboratory support tool providing all necessary reagents, quality control samples, calibrators, and consumables required for the LC-MS\/MS based quantification of Angiotensin I, Angiotensin II and Aldosterone in clinical samples. An optional software tool can be used to calculate angiotensin-based biomarkers that have been validated to screen for secondary causes of hypertension and to monitor antihypertensive drug efficacy.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6c4fda1 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"6c4fda1\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3a5014e\" data-id=\"3a5014e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5299480 elementor-widget elementor-widget-heading\" data-id=\"5299480\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\"><p style=\"text-align: center;\"><span style=\"font-family: var( --e-global-typography-primary-font-family ), Sans-serif; font-size: 26px; font-weight: var( --e-global-typography-primary-font-weight );\"><font color=\"#ffffff\">Process overview<\/font><\/span><span style=\"font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-size: 22px; font-weight: var( --e-global-typography-text-font-weight );\"><\/span><\/p><\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8c59206 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"8c59206\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-f4343dd\" data-id=\"f4343dd\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9af8340 e-transform elementor-widget elementor-widget-image\" data-id=\"9af8340\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:0.7,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:0.7,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"277\" src=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2023\/05\/workflow_icons_no-1024x277.png\" class=\"attachment-large size-large wp-image-4794\" alt=\"\" srcset=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2023\/05\/workflow_icons_no-980x265.png 980w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2023\/05\/workflow_icons_no-480x130.png 480w\" sizes=\"auto, (min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1024px, 100vw\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-956b18c elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"956b18c\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-63c9d04\" data-id=\"63c9d04\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e55cee0 elementor-widget elementor-widget-text-editor\" data-id=\"e55cee0\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>RAAS Triple-A\u2122 analysis requires the collection of a serum sample of at least 0.5 ml. Patients should be on their standard antihypertensive treatment. With a bench stability of at least 8 hours at room temperature, the assay is highly robust and compatible with routine laboratory procedures. Samples may optionally be shipped or stored frozen until analysis, allowing interval workup of clinical routine samples as well as retrospective assessment of study samples, if needed.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-81f203a elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"81f203a\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-b7e02be\" data-id=\"b7e02be\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f8f9059 elementor-widget elementor-widget-heading\" data-id=\"f8f9059\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\"><p style=\"text-align: center;\"><span style=\"font-family: var( --e-global-typography-primary-font-family ), Sans-serif; font-size: 26px; font-weight: var( --e-global-typography-primary-font-weight );\"><font color=\"#ffffff\">More information<\/font><\/span><span style=\"font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-size: 22px; font-weight: var( --e-global-typography-text-font-weight );\"><\/span><\/p><\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-021138f elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"021138f\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-9f4fc66\" data-id=\"9f4fc66\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d3fb8e7 e-transform e-transform elementor-widget elementor-widget-image\" data-id=\"d3fb8e7\" data-element_type=\"widget\" data-settings=\"{&quot;_transform_translateY_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:-12,&quot;sizes&quot;:[]},&quot;_transform_scale_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:1.02,&quot;sizes&quot;:[]},&quot;_transform_translateX_effect&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_translateX_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_translateX_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_translateY_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_translateY_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_tablet&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]},&quot;_transform_scale_effect_mobile&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1200\" height=\"875\" src=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/poster.jpg\" class=\"attachment-2048x2048 size-2048x2048 wp-image-2994\" alt=\"\" srcset=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/poster.jpg 1200w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/poster-980x715.jpg 980w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/poster-480x350.jpg 480w\" sizes=\"auto, (min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1200px, 100vw\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-63da7ad elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"63da7ad\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-cb3854b\" data-id=\"cb3854b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1b4bb4c elementor-widget elementor-widget-text-editor\" data-id=\"1b4bb4c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h1><span style=\"color: #004874;\">More research using our technology for RAAS profiling can be found <span style=\"color: #ff6600;\"><a style=\"color:#e98406;\" href=\"https:\/\/raastriple-a.com\/de\/publications\/\" target=\"_blank\" rel=\"noopener\">here<\/a><\/span><\/span><\/h1>\n<div id=\"gtx-trans\" style=\"position: absolute; left: 444px; top: 91.1406px;\">\n<div class=\"gtx-trans-icon\">&nbsp;<\/div>\n<\/div>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1d629ad elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"1d629ad\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-20a5c17\" data-id=\"20a5c17\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f4f40fc elementor-widget elementor-widget-heading\" data-id=\"f4f40fc\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\"><p><span style=\"color: #ffffff;\">Contact our customer support team to learn more and receive LC-MS\/MS system specific information.<\/span><\/p>\n<p><span style=\"color: #ffffff;\">Get RAAS Triple-A\u2122 started in your laboratory!<\/span><span style=\"font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-size: 22px; font-weight: var( --e-global-typography-text-font-weight );\"><\/span><\/p><\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-14f6683 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"14f6683\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d5cc511\" data-id=\"d5cc511\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c4cbeb3 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"c4cbeb3\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-b099ba9\" data-id=\"b099ba9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3740a87 elementor-widget elementor-widget-spacer\" data-id=\"3740a87\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.12.1 - 02-04-2023 *\/\n.elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-con{--container-widget-width:100%}.e-con-inner>.elementor-widget-spacer,.e-con>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));--align-self:var(--container-widget-align-self,initial);--flex-shrink:0}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container,.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer,.e-con>.elementor-widget-spacer>.elementor-widget-container,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-con-inner>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner,.e-con>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))}<\/style>\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-44b8311 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"44b8311\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e94efed\" data-id=\"e94efed\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-96df8c7 elementor-widget elementor-widget-text-editor\" data-id=\"96df8c7\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h1><span style=\"color: #e98406;\">Register for our newsletter<\/span><\/h1>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e592c8a elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"e592c8a\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-29f0da0\" data-id=\"29f0da0\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column 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type=\"hidden\" name=\"current_url\" value=\"https:\/\/raastriple-a.com\/de\/doctors\/\"><input type=\"hidden\" name=\"render_id\" value=\"0\"><input type=\"hidden\" name=\"action\" value=\"forminator_submit_form_custom-forms\"><label for=\"input_2\" class=\"forminator-hidden\" aria-hidden=\"true\">Bitte f\u00fclle dieses Feld nicht aus. <input id=\"input_2\" type=\"text\" name=\"input_2\" value=\"\" autocomplete=\"off\"><\/label><input type=\"hidden\" name=\"trp-form-language\" value=\"de\"\/><\/form>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-ae94d64\" data-id=\"ae94d64\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2b3f663 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"2b3f663\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a546722\" data-id=\"a546722\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>A unique lab test for hypertension profiling Hypertension as the main risk for cardiovascular events Uncontrolled hypertension affects more than 50% of patients treated for their high blood pressure. Underlying causes are manifold and it is therefore challenging to identify the cause of inefficient blood pressure lowering therapy in clinical practice. Diagnostic tools that have [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"<style>\/*! elementor - v3.7.7 - 20-09-2022 *\/\n.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=\".svg\"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"1024\" height=\"474\" src=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/08\/doctor_banner-1024x474.png\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/08\/doctor_banner-1024x474.png 1024w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/08\/doctor_banner-300x139.png 300w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/08\/doctor_banner-768x356.png 768w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/08\/doctor_banner-1536x711.png 1536w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/08\/doctor_banner-18x8.png 18w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/08\/doctor_banner-1080x500.png 1080w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/08\/doctor_banner-1280x593.png 1280w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/08\/doctor_banner-980x454.png 980w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/08\/doctor_banner-480x222.png 480w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/08\/doctor_banner-1320x611.png 1320w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/08\/doctor_banner-600x278.png 600w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/08\/doctor_banner.png 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t<style>\/*! elementor - v3.7.7 - 20-09-2022 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h2><h1 style=\"text-align: left;\">A unique lab test for <\/h1>\n<h1 style=\"text-align: left;\">hypertension profiling<\/h1><\/h2>\t\t\n\t\t\t<h3><p style=\"text-align: center;\"><font color=\"#ffffff\">Hypertension as the main risk for cardiovascular events<\/font><\/p><\/h3>\t\t\n\t\t<p>Uncontrolled hypertension affects more than 50% of patients treated for their high blood pressure. Underlying causes are manifold and it is therefore challenging to identify the cause of inefficient blood pressure lowering therapy in clinical practice. Diagnostic tools that have been available so far to screen for frequent forms of secondary hypertension, like primary aldosteronism, suffer from interference with anti-hypertensive therapies and require drug withdrawal before screening, leading to very low screening rates. However, more than every 10th high blood pressure patient is affected by primary aldosteronism. General practitioners frequently have to go the trial and error path when seeking to control hypertension in their patients.\u00a0Without knowing the underlying molecular causes, this might result in frustration among patients, inappropriate drug prescriptions and also increases in the overall cardiovascular risk due to a long time to blood pressure control.<\/p>\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"335\" height=\"411\" src=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/hypertonie.png\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/hypertonie.png 335w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/hypertonie-245x300.png 245w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/hypertonie-10x12.png 10w\" sizes=\"(max-width: 335px) 100vw, 335px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t<h3><p style=\"text-align: center;\"><font color=\"#ffffff\">What is RAAS Triple-A\u2122 analysis?<\/font><\/p><\/h3>\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"597\" height=\"505\" src=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/angiotensin_diagram.png\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/angiotensin_diagram.png 597w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/angiotensin_diagram-300x254.png 300w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/angiotensin_diagram-14x12.png 14w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/angiotensin_diagram-480x406.png 480w\" sizes=\"(max-width: 597px) 100vw, 597px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t<p>The Renin-Angiotensin-Aldosterone-System (RAAS) is critically involved in the regulation of fluid balance and blood pressure. It serves as a major target for the pharmacologic treatment of hypertension. The RAAS Triple-A\u2122 hormones (Angiotensin I, Angiotensin II and Aldosterone) and their receptors represent key molecular players in mediating physiologic hormonal effects.<\/p><p>Up until now, the laboratory evaluation of the RAAS has been primarily based on measuring Renin, which is the upstream precursor of Angiotensin II, the actual effector hormone of the RAAS. Recent doubts related to the reliability of such methods led to a surge in clinical LC-MS\/MS for Aldosterone, while an LC-MS\/MS based method for the simultaneous measurement of Renin is still not available yet.<\/p><p>For the first time, RAAS-Triple-A\u2122\u00a0analysis, and subsequent calculation of Angiotensin-based biomarkers paved the way for the simultaneous LC-MS\/MS based assessment of Aldosterone concentration, renin activity and ACE activity in standard serum samples. This allows for an in-depth assessment of RAAS dynamics, which includes screening for secondary hypertension (primary aldosteronism, PA) using the Aldosterone-to-Angiotensin II ratio (AA2-R).<\/p>\t\t\n\t\t\t<h3><p style=\"text-align: center;\"><font color=\"#ffffff\">Angiotensin-based biomarkers<\/font><\/p><\/h3>\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"250\" height=\"180\" src=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/PRA_S.png\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/PRA_S.png 250w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/PRA_S-18x12.png 18w\" sizes=\"(max-width: 250px) 100vw, 250px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"250\" height=\"180\" src=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/ACE_S.png\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/ACE_S.png 250w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/ACE_S-18x12.png 18w\" sizes=\"(max-width: 250px) 100vw, 250px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"250\" height=\"180\" src=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/AA2_Ratio.png\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/AA2_Ratio.png 250w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/AA2_Ratio-18x12.png 18w\" sizes=\"(max-width: 250px) 100vw, 250px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t<p><strong>PRA-S:<\/strong>\u00a0Angiotensin based marker for renin, the pacemaker enzyme of the Renin-Angiotensin-Aldosterone system (RAAS).\u00a0<\/p><p>Renin is secreted by the kidney and is regulated by renal hemodynamics, fluid and salt balance as well as Angiotensin II itself.\u00a0Most antihypertensive drugs have direct or indirect effects on Renin secretion.<\/p><p><strong>ACE-S:<\/strong>\u00a0Angiotensin based marker for the activity of Angiotensin converting enzyme (ACE), which is the main vascular and systemic producer of Angiotensin II. ACE-S is obtained by calculating the ratio between Angiotensin II and Angiotensin I.\u00a0ACE-S in a patient sample is a measure for the pharmacologic efficacy of an ongoing ACE inhibitor therapy.<\/p><p><strong>AA2-Ratio:<\/strong>\u00a0The ratio of Aldosterone to Angiotensin II reflects the responsiveness of adrenal glands for Angiotensin II. In primary aldosteronism, which affects up to 10 % of hypertensive patients, this ratio is increased because excess Aldosterone secretion is largely independent of Angiotensin II. In patients with essential hypertension treated with ARBs, the AA2-Ratio is suppressed and can be used to monitor drug efficacy<\/p>\t\t\n\t\t\t<h3><p style=\"text-align: center;\"><font color=\"#ffffff\">RAAS Triple-A\u2122 Kit<\/font><\/p><\/h3>\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"576\" height=\"475\" src=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/tubebox_v2_gray130722.png\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/tubebox_v2_gray130722.png 576w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/tubebox_v2_gray130722-300x247.png 300w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/tubebox_v2_gray130722-480x396.png 480w\" sizes=\"(max-width: 576px) 100vw, 576px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t<p>The RAAS Triple-A\u2122 kit (CE-IVD) is a powerful routine laboratory support tool providing all necessary reagents, quality control samples, calibrators, and consumables required for the LC-MS\/MS based quantification of Angiotensin I, Angiotensin II and Aldosterone in clinical samples. An optional software tool can be used to calculate angiotensin-based biomarkers that have been validated to screen for secondary causes of hypertension and to monitor antihypertensive drug efficacy.<\/p>\t\t\n\t\t\t<h3><p style=\"text-align: center;\"><font color=\"#ffffff\">Process overview<\/font><\/p><\/h3>\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"1024\" height=\"277\" src=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/workflow_progress_icons-1024x277.png\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/workflow_progress_icons-1024x277.png 1024w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/workflow_progress_icons-300x81.png 300w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/workflow_progress_icons-768x207.png 768w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/workflow_progress_icons-1536x415.png 1536w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/workflow_progress_icons-2048x553.png 2048w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/workflow_progress_icons-18x5.png 18w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/workflow_progress_icons-1080x292.png 1080w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/workflow_progress_icons-1280x346.png 1280w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/workflow_progress_icons-980x265.png 980w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/workflow_progress_icons-480x130.png 480w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/workflow_progress_icons-1320x357.png 1320w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t<p>RAAS Triple-A\u2122 analysis requires the collection of a serum sample of at least 0.5 ml. Patients should be on their standard antihypertensive treatment. With a bench stability of at least 8 hours at room temperature, the assay is highly robust and compatible with routine laboratory procedures. Samples may optionally be shipped or stored frozen until analysis, allowing interval workup of clinical routine samples as well as retrospective assessment of study samples, if needed.<\/p>\t\t\n\t\t\t<h3><p style=\"text-align: center;\"><font color=\"#ffffff\">More information<\/font><\/p><\/h3>\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"1080\" height=\"788\" src=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/poster.jpg\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/poster.jpg 1200w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/poster-300x219.jpg 300w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/poster-1024x747.jpg 1024w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/poster-768x560.jpg 768w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/poster-16x12.jpg 16w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/poster-1080x788.jpg 1080w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/poster-980x715.jpg 980w, https:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/10\/poster-480x350.jpg 480w\" sizes=\"(max-width: 1080px) 100vw, 1080px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t<h1>More research using our technology for RAAS profiling can be found <a style=\"color:#e98406;\" href=\"https:\/\/raastriple-a.com\/publications\/\" target=\"_blank\" rel=\"noopener\">here<\/a><\/h1>\n&nbsp;\n\t\t\t<h3><p>Contact our customer support team to learn more and receive LC-MS\/MS system specific information.<\/p>\n<p>Get RAAS Triple-A\u2122 started in your laboratory!<\/p><\/h3>\t\t\n\t\t\t<style>\/*! elementor - v3.7.7 - 20-09-2022 *\/\n.elementor-column .elementor-spacer-inner{height:var(--spacer-size)}.e-container{--container-widget-width:100%}.e-container>.elementor-widget-spacer{width:var(--container-widget-width,var(--spacer-size));-ms-flex-item-align:stretch;align-self:stretch;-ms-flex-negative:0;flex-shrink:0}.e-container>.elementor-widget-spacer>.elementor-widget-container,.e-container>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer{height:100%}.e-container>.elementor-widget-spacer>.elementor-widget-container>.elementor-spacer>.elementor-spacer-inner{height:var(--container-widget-height,var(--spacer-size))}<\/style>\t\t\n\t\t<h1>Register for our newsletter<\/h1>","_et_gb_content_width":"","footnotes":""},"class_list":["post-1168","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/raastriple-a.com\/de\/wp-json\/wp\/v2\/pages\/1168","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/raastriple-a.com\/de\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/raastriple-a.com\/de\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/raastriple-a.com\/de\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/raastriple-a.com\/de\/wp-json\/wp\/v2\/comments?post=1168"}],"version-history":[{"count":286,"href":"https:\/\/raastriple-a.com\/de\/wp-json\/wp\/v2\/pages\/1168\/revisions"}],"predecessor-version":[{"id":4797,"href":"https:\/\/raastriple-a.com\/de\/wp-json\/wp\/v2\/pages\/1168\/revisions\/4797"}],"wp:attachment":[{"href":"https:\/\/raastriple-a.com\/de\/wp-json\/wp\/v2\/media?parent=1168"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}