{"id":3280,"date":"2022-10-11T14:08:44","date_gmt":"2022-10-11T14:08:44","guid":{"rendered":"https:\/\/raastriple-a.com\/?page_id=3280"},"modified":"2022-10-12T07:08:57","modified_gmt":"2022-10-12T07:08:57","slug":"publications","status":"publish","type":"page","link":"https:\/\/raastriple-a.com\/de\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"3280\" class=\"elementor elementor-3280\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-58df6a87 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"58df6a87\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2693fa92\" data-id=\"2693fa92\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b4647ef elementor-widget elementor-widget-heading\" data-id=\"b4647ef\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.12.1 - 02-04-2023 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h2 class=\"elementor-heading-title elementor-size-default\"><h1 style=\"text-align: left;\"><span style=\"color: #004874;\">Publication <\/span><\/h1><\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3576802 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"3576802\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-34bcce5\" data-id=\"34bcce5\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-66d990c elementor-widget elementor-widget-heading\" data-id=\"66d990c\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\"><p style=\"text-align: center;\"><span style=\"font-family: var( --e-global-typography-primary-font-family ), Sans-serif; font-size: 26px; font-weight: var( --e-global-typography-primary-font-weight );\"><font color=\"#ffffff\">More research using our technology for RAAS profiling <\/font><\/span><span style=\"font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-size: 22px; font-weight: var( --e-global-typography-text-font-weight );\"><\/span><\/p><\/h3>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e8f98a3 elementor-section-boxed elementor-section-height-default elementor-section-height-default wpr-particle-no wpr-jarallax-no wpr-parallax-no wpr-sticky-section-no\" data-id=\"e8f98a3\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3bcc51f\" data-id=\"3bcc51f\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f98c5b4 elementor-tabs-view-horizontal elementor-widget elementor-widget-tabs\" data-id=\"f98c5b4\" data-element_type=\"widget\" data-widget_type=\"tabs.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>.elementor-widget-tabs.elementor-tabs-view-vertical 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(min-width:701px){.elementor-widget-tabs.elementor-tabs-view-vertical .elementor-tabs{display:flex}.elementor-widget-tabs.elementor-tabs-view-vertical .elementor-tabs-wrapper{flex-direction:column}.elementor-widget-tabs.elementor-tabs-view-vertical .elementor-tabs-content-wrapper{flex-grow:1;border-style:solid solid solid none}.elementor-widget-tabs.elementor-tabs-view-horizontal .elementor-tab-content{border-style:none solid solid}.elementor-widget-tabs.elementor-tabs-alignment-center .elementor-tabs-wrapper,.elementor-widget-tabs.elementor-tabs-alignment-end .elementor-tabs-wrapper,.elementor-widget-tabs.elementor-tabs-alignment-stretch .elementor-tabs-wrapper{display:flex}.elementor-widget-tabs.elementor-tabs-alignment-center .elementor-tabs-wrapper{justify-content:center}.elementor-widget-tabs.elementor-tabs-alignment-end .elementor-tabs-wrapper{justify-content:flex-end}.elementor-widget-tabs.elementor-tabs-alignment-stretch.elementor-tabs-view-horizontal .elementor-tab-title{width:100%}.elementor-widget-tabs.elementor-tabs-alignment-stretch.elementor-tabs-view-vertical .elementor-tab-title{height:100%}.elementor-tabs .elementor-tab-mobile-title{display:none}}<\/style>\t\t<div class=\"elementor-tabs\">\n\t\t\t<div class=\"elementor-tabs-wrapper\" role=\"tablist\" >\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-2611\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"elementor-tab-content-2611\" aria-expanded=\"false\">2022<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-2612\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2612\" aria-expanded=\"false\">2021<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-2613\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2613\" aria-expanded=\"false\">2020<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-2614\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"4\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2614\" aria-expanded=\"false\">2019<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-2615\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"5\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2615\" aria-expanded=\"false\">2018<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-2616\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"6\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2616\" aria-expanded=\"false\">2017<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-2617\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"7\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2617\" aria-expanded=\"false\">2016<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-2618\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"8\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2618\" aria-expanded=\"false\">2015<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-2619\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"9\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2619\" aria-expanded=\"false\">2014<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-26110\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"10\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-26110\" aria-expanded=\"false\">2013<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-26111\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"11\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-26111\" aria-expanded=\"false\">2012<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t<div class=\"elementor-tabs-content-wrapper\" role=\"tablist\" aria-orientation=\"vertical\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"elementor-tab-content-2611\" aria-expanded=\"false\">2022<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-2611\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-2611\" tabindex=\"0\" hidden=\"false\"><div class=\"divider-wrap\" data-alignment=\"default\">\u00a0<span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Briand et at. <\/span><strong style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">Diet-Induced Obesity and NASH Impair Disease Recovery in SARS-CoV-2-Infected Golden Hamsters.<\/strong><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\"> Viruses. 2022 Sep 17;14(9):2067. PUBMED: <\/span><a style=\"font-size: 14px; font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36146875\/\">36146875<\/a><br \/><br \/><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Cruz-L\u00f3pez et al.<\/span><strong style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\"> Blood pressure-independent renoprotective effects of small interference RNA targeting liver angiotensinogen in experimental diabetes.<\/strong><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\"> Br J Pharmacol. 2022 Sep 15. PUBMED: <\/span><a style=\"font-size: 14px; font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36106615\/\">36106615<\/a><br \/><br \/><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Simko et at. <\/span><strong style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">Sacubitril\/Valsartan and Ivabradine Attenuate Left Ventricular Remodelling and Dysfunction in Spontaneously Hypertensive Rats: Different Interactions with the Renin-Angiotensin-Aldosterone System. <\/strong><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Biomedicines. 2022 Jul 31;10(8):1844. PUBMED: <\/span><a style=\"font-size: 14px; font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36009391\/\">36009391<\/a><br \/><br \/><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">D\u00f6rr et al. <\/span><strong style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">The Effect of FGF23 on Cardiac Hypertrophy Is Not Mediated by Systemic Renin-Angiotensin- Aldosterone System in Hemodialysis. <\/strong><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Front Med (Lausanne). 2022 Apr 26;9:878730. PUBMED: <\/span><a style=\"font-size: 14px; font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35559350\/\">35559350<\/a><br \/><br \/><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Krenn et al. <\/span><strong style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">The Renin-Angiotensin System as a Component of Biotrauma in Acute Respiratory Distress Syndrome.<\/strong><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\"> Front. Physiol., 13 April 2022. PUBMED: <\/span><a style=\"font-size: 14px; font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35498160\/\">35498160<\/a><br \/><br \/><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Lourenco et at. <\/span><strong style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">Characterization of the intrarenal renin-angiotensin system in cats with naturally occurring chronic kidney disease. <\/strong><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">J Vet Intern Med. 2022 Mar;36(2):647-655. PUBMED: <\/span><a style=\"font-size: 14px; font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35352404\/\">35352404<\/a><br \/><br \/><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Ward et al. <\/span><strong style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">Circulating renin-angiotensin-aldosterone system activity in cats with systemic hypertension or cardiomyopathy. <\/strong><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">J Vet Intern Med. 2022 Mar 14. PUBMED: <\/span><a style=\"font-size: 14px; font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35285549\/\">35285549<\/a><br \/><br \/><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Mao et al. <\/span><strong style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">Tidal Volume-Dependent Activation of the Renin-Angiotensin System in Experimental Ventilator-Induced Lung Injury.<\/strong><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\"> Crit Care Med. 2022 Feb 22. PUBMED: <\/span><a style=\"font-size: 14px; font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35191411\/\">35191411<\/a><br \/><br \/><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Wang et al. <\/span><strong style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">Dysregulation of ACE (Angiotensin-Converting Enzyme)-2 and Renin-Angiotensin Peptides in SARS-CoV-2 Mediated Mortality and End-Organ Injuries.<\/strong><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\"> Hypertension . 2022 Feb;79(2):365-378. PUBMED ID: <\/span><a style=\"font-size: 14px; font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34844421\/\">34844421<\/a><br \/><br \/><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Antlanger et al. <\/span><strong style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">Combined SGLT-2 and ACE inhibition upregulates the renin-angiotensin system in chronic kidney disease with type 2 diabetes: Results of a randomized, double-blind, placebo-controlled exploratory trial.<\/strong><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\"> Diabetes Obes Metab. 2022 Jan 4. PUBMED ID: <\/span><a style=\"font-size: 14px; font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34984822\/\">34984822<\/a><\/div><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2612\" aria-expanded=\"false\">2021<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-2612\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"2\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-2612\" tabindex=\"0\" hidden=\"hidden\"><div class=\"toggle accent-color\" data-inner-wrap=\"true\">\n<h3><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Evans et al. <\/span><strong style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">Suspected primary hyperreninism in a cat with malignant renal sarcoma and global renin-angiotensin-aldosterone system upregulation.<\/strong><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\"> J Vet Intern Med. 2021 Dec 3. PUBMED ID: <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34859924\/\" style=\"font-size: 14px; font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">34859924<\/a><br><\/h3><div><div class=\"inner-toggle-wrap\"><div class=\"wpb_text_column wpb_content_element\"><div class=\"wpb_wrapper\">\n<p>Krenn et al. <strong>Equilibrium Angiotensin Metabolite Profiling in Patients with Acute Respiratory Distress Syndrome Indicates Angiotensin-Converting Enzyme Inhibition.<\/strong> Am J Respir Crit Care Med. 2020 Nov 15;202(10):1468-1471. PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32628511\/\">32628511<\/a><\/p>\n<p>Kovarik et al.<strong> Effect of Mineralocorticoid Receptor Antagonism and ACE Inhibition on Angiotensin Profiles in Diabetic Kidney Disease: An Exploratory Study.<\/strong> Diabetes Ther. 2021 Sep;12(9):2485-2498. PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34351585\/\">34351585<\/a><\/p>\n<p>Alves-Lopes et al. <strong>Selective Inhibition of the C-Domain of ACE (Angiotensin-Converting Enzyme) Combined With Inhibition of NEP (Neprilysin): A Potential New Therapy for Hypertension.<\/strong> Hypertension. 2021 Sep;78(3):604-616. PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34304582\/\">34304582<\/a><\/p>\n<p>van Rooyen et al. <strong>Aldosterone and angiotensin II profiles in young black and white women using different hormonal contraceptives: the African-PREDICT study.<\/strong> J Hum Hypertens. 2021 Jun 25. PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34172825\/\">34172825<\/a><\/p>\n<p>Binder et al. <strong>Renin Feedback Is an Independent Predictor of Outcome in HFpEF.<\/strong> J Pers Med. 2021 May 3;11(5):370. PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34063595\/\">34063595<\/a><\/p>\n<p>Nonn et at. <strong>Maternal Angiotensin Increases Placental Leptin in Early Gestation via an Alternative Renin-Angiotensin System Pathway: Suggesting a Link to Preeclampsia.<\/strong> Hypertension. 2021 May 5;77(5):1723-1736. PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33775117\/\">33775117<\/a><\/p>\n<p>Kukida et al. <strong>Effects of Endogenous Angiotensin II on Abdominal Aortic Aneurysms and Atherosclerosis in Angiotensin II-Infused Mice. <\/strong>J Am Heart Assoc. 2021 May 4;10(9):e020467. PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33890483\/\">33890483<\/a><\/p>\n<p>Pavo et al. <strong>Myocardial Angiotensin Metabolism in End-Stage Heart Failure.<\/strong> J Am Coll Cardiol. 2021 Apr 13;77(14):1731-1743. PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33832600\/\">33832600<\/a><\/p>\n<p>Bov\u00e9e et al. <strong>Renoprotective Effects of Small Interfering RNA Targeting Liver Angiotensinogen in Experimental Chronic Kidney Disease.<\/strong> Hypertension. 2021 May 5;77(5):1600-1612. PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33719507\/\">33719507<\/a><\/p>\n<p>Vischer et al. <strong>Influence of Antihypertensive Treatment on RAAS Peptides in Newly Diagnosed Hypertensive Patients.<\/strong> Cells. 2021 Mar 3;10(3):534. PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33802464\/\">33802464<\/a><\/p>\n<p>Carrocia et al. <strong>Aldosterone and cortisol synthesis regulation by angiotensin-(1-7) and angiotensin-converting enzyme 2 in the human adrenal cortex.<\/strong> J Hypertens. 2021 Mar 1. PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33657582\/\">33657582<\/a><\/p>\n<p>Reindl-Schwaighofer et al. <strong>Angiotensin-Converting Enzyme 2 (ACE2) Elevation in Severe COVID-19<\/strong>. Am J Respir Crit Care Med. 2021 Feb 18. PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33600742\/\">33600742<\/a><\/p>\n<p>van Lier et al. <strong>Increased blood angiotensin converting enzyme 2 activity in critically ill COVID-19 patients.<\/strong> ERJ Open Res. 2021 Mar 15;7(1):00848-2020. PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33738305\/\">33738305<\/a><\/p>\n<p>Batchu et al. <strong>Lung and Kidney ACE2 and TMPRSS2 in Renin-Angiotensin System Blocker-Treated Comorbid Diabetic Mice Mimicking Host Factors That Have Been Linked to Severe COVID-19. <\/strong>Diabetes. 2021 Mar;70(3):759-771 PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33310740\/\">33310740<\/a><\/p>\n<p>Kutz et al. <strong>Renin-Angiotensin-Aldosterone System peptide profiles in patients with COVID-19.<\/strong> Eur J Endocrinol. 2021 Feb 1;EJE-20-1445.R1 PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33539316\/\">33539316<\/a><\/p>\n<p>Uijl et al. <strong>No evidence for brain renin-angiotensin system activation during DOCA-salt hypertension.<\/strong> Clin Sci (Lond). 2021 Jan 6;CS20201239. PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33404046\/\">33404046<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2613\" aria-expanded=\"false\">2020<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-2613\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"3\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-2613\" tabindex=\"0\" hidden=\"hidden\"><div class=\"toggle accent-color\" data-inner-wrap=\"true\">\n<h3><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Huh et al. <\/span><strong style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">Effect of angiotensin receptor blockers and angiotensin-converting enzyme 2 on plasma equilibrium angiotensin peptide concentrations in cats with heart disease. <\/strong><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">J Vet Intern Med. 2020 Nov 2. PUBMED ID: <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33135833\/\" style=\"font-size: 14px; font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">33135833<\/a><br><\/h3><div><div class=\"inner-toggle-wrap\"><div class=\"wpb_text_column wpb_content_element\"><div class=\"wpb_wrapper\">\n<p>Gafane-Matemane et al. <strong>Associations of central and peripheral blood pressure with the renin-angiotensin-aldosterone system in healthy young adults: the African-PREDICT study. <\/strong>Hypertens Res. 2020 Oct 30. PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33122821\/\">33122821<\/a><\/p>\n<p>Zoufaly et al. <strong>Human recombinant soluble ACE2 in severe COVID-19<\/strong>. Lancet Respir Med. September 24, 2020. <a href=\"https:\/\/www.thelancet.com\/pdfs\/journals\/lanres\/PIIS2213-2600(20)30418-5.pdf\">doi.org\/10.1016\/<\/a><br>S2213-2600(20)30418-5.<\/p>\n<p>Kintscher et al. <strong>Plasma Angiotensin Peptide Profiling and ACE (Angiotensin-Converting Enzyme)-2 Activity in COVID-19 Patients Treated With Pharmacological Blockers of the Renin-Angiotensin System. <\/strong>Hypertension. 2020 Nov;76(5):e34-e36. doi: 10.1161\/HYPERTENSIONAHA.120.15841. PUMBED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32851897\/\">32851897<\/a><\/p>\n<p>De Souza et al. <strong>Persistent Renin-Angiotensin System Sensitization Months After Body Weight Recovery From Severe Food Restriction in Female Fischer Rats. <\/strong>J Am Heart Assoc. 2020 Jul 21;9(14):e017246. PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32674648\/\">32674648<\/a><\/p>\n<p>Messmann et al. <strong>Alterations of the renin angiotensin system in human end-stage heart failure before and after mechanical cardiac unloading by LVAD support. <\/strong>Mol Cell Biochem. 2020 Jun 20. doi: 10.1007\/s11010-020-03787-7 PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32564294\/\">32564294<\/a><\/p>\n<p>Krenn et al. <strong>Equilibrium Angiotensin Metabolite Profiling in Patients with Acute Respiratory Distress Syndrome Indicates Angiotensin Converting Enzyme Inhibition. <\/strong>Am J Respir Crit Care Med. 2020 Jul 6. doi: 10.1164\/rccm.201912-2504LE PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32628511\/\">32628511<\/a><\/p>\n<p>Wang et al. <strong>Elevated Angiotensin 1-7\/Angiotensin II Ratio Predicts Favorable Outcomes in Patients With Heart Failure<\/strong>. Circ Heart Fail. 2020 Jul;13(7):e006939. doi: 10.1161\/CIRCHEARTFAILURE.120.006939. Epub 2020 Jun 25. PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32580658\/\">32580658<\/a><\/p>\n<p>Shalinee et al. <strong>Dipeptidyl peptidase 3 modulates the renin-angiotensin system in mice. <\/strong>J Biol Chem. 2020 Jun 16;jbc.RA120.014183. doi: 10.1074\/jbc.RA120.014183. PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32546481\/\">32546481<\/a><\/p>\n<p>Guo et al. <strong>Effects of Ramipril on the Aldosterone\/Renin Ratio and the Aldosterone\/Angiotensin II Ratio in Patients With Primary Aldosteronism.<\/strong> Hypertension. 2020 Jun 8;HYPERTENSIONAHA12014871. PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32507039\">32507039<\/a><\/p>\n<p>Kaltenecker et al. <strong>Critical Role of Neprilysin in Kidney Angiotensin Metabolism.<\/strong> Circ Res. 2020 May 18. doi: 10.1161\/CIRCRESAHA.119.316151. 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PUBMED ID: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32112596\">32112596 <\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"4\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2614\" aria-expanded=\"false\">2019<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-2614\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"4\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-2614\" tabindex=\"0\" hidden=\"hidden\"><div class=\"toggle accent-color\" data-inner-wrap=\"true\">\n<h3><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Manis et al. <\/span><strong style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">Relationship Between Renin-Angiotensin-Aldosterone System and Renal Kir5.1 Channels.<\/strong><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\"> Clin Sci (Lond). 2019;CS20190876. 2019 Dec 4 PUBMED ID: <\/span><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31799617\" style=\"font-size: 14px; font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">31799617<\/a><br><\/h3><div><div class=\"inner-toggle-wrap\"><div class=\"wpb_text_column wpb_content_element\"><div class=\"wpb_wrapper\">\n<p>Potter et al. <strong>Comparison between the effects of torsemide and furosemide on the renin-angiotensin-aldosterone system of normal dogs.<\/strong> J Vet Cardiol. 2019 Dec;26:51-62. doi: 10.1016\/j.jvc.2019.11.003. Epub 2019 Nov 14. PUBMED ID: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31809955\">31809955 <\/a><\/p>\n<p>Burrello et al. <strong>Renin-Angiotensin-Aldosterone System Triple-A Analysis for the Screening of Primary Aldosteronism.<\/strong> Hypertension HYPERTENSIONAHA11913772 2019 Nov 25 PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31760886\">31760886<\/a><\/p>\n<p>van Rooyen et al. <strong>A Primary Aldosteronism-Like Phenotype Identified With the Aldosterone-To-Angiotensin II Ratio in Black Men. <\/strong>The SABPA StudyCardiovasc J Afr, 30, 1-6 2019 Nov 27. PUBMED ID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31781716\">31781716<\/a><\/p>\n<p>G\u00f6ppner et al. <strong>Pathogenesis of hypertension in a mouse model for human CLCN2 related hyperaldosteronism. <\/strong>Nat Commun. 2019 Oct 15;10(1):4678. 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PUBMED ID: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31278281\">31278281<\/a><\/p>\n<p>Binder et al. <strong>Angs (Angiotensins) of the Alternative Renin-Angiotensin System Predict Outcome in Patients With Heart Failure and Preserved Ejection Fraction. <\/strong>Hypertension. 2019 Jun 24:HYPERTENSIONAHA11912786. doi: 10.1161\/HYPERTENSIONAHA.119.12786. PUBMED ID: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31230551\">31230551<\/a><\/p>\n<p>Larouche-Lebel et al. <strong>Plasma and tissue angiotensin-converting enzyme 2 activity and plasma equilibrium concentrations of angiotensin peptides in dogs with heart disease. <\/strong>J Vet Intern Med. 2019 Jun 28. doi: 10.1111\/jvim.15548. PUBMED ID: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31254308\">31254308<\/a><\/p>\n<p>Wang et al. <strong>Apelin protects against abdominal aortic aneurysm and the therapeutic role of neutral endopeptidase resistant apelin analogs. <\/strong>Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):13006-13015. doi: 10.1073\/pnas.1900152116. Epub 2019 Jun 12. PUBMED ID: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31189595\">31189595 <\/a><\/p>\n<p>Caroccia et al. <strong>Aldosterone Stimulates Its Biosynthesis Via A Novel GPER Mediated Mechanism.<\/strong> J Clin Endocrinol Metab. 2019 May 24. pii: jc.2019-00043. doi: 10.1210\/jc.2019-00043. PUBMED ID: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31125081\">31125081<\/a><\/p>\n<p>Wolf et al. <strong>Identifying a disease specific renin-angiotensin-aldosterone system fingerprint in patients with primary adrenal insufficiency. <\/strong>Eur J Endocrinol. 2019 May 1. pii: EJE-19-0086.R1. doi: 10.1530\/EJE-19-0086. PUBMED ID: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31075757\">31075757<\/a><\/p>\n<p>Uijl et al. <strong>Strong and Sustained Antihypertensive Effect of Small Interfering RNA Targeting Liver Angiotensinogen. <\/strong>Hypertension. 2019 Jun;73(6):1249-1257. doi: 10.1161\/HYPERTENSIONAHA.119.12703. PUBMED ID: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31030610\">31030610<\/a><\/p>\n<p>Kopecky et al. <strong>Molecular regulation of the renin-angiotensin system by sodium-glucose cotransporter 2 inhibition in type 1 diabetes mellitus. <\/strong>Diabetologia. 2019 Apr 11. doi: 10.1007\/s00125-019-4871-8. PUBMED ID: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30976852\">30976852<\/a> <b><\/b><\/p>\n<p>Ames et al. <strong>The renin-angiotensin-aldosterone system and its suppression. <\/strong>J Vet Intern Med. 2019 Mar;33(2):363-382. doi: 10.1111\/jvim.15454. Epub 2019 Feb 26. PUBMED ID: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30806496\">30806496<\/a><\/p>\n<p>Ilatovskaya et al. <strong>Salt-deficient diet exacerbates cystogenesis in ARPKD via epithelial sodium channel (ENaC). <\/strong>EBioMedicine. 2019 Feb;40:663-674. doi: 10.1016\/j.ebiom.2019.01.006. Epub 2019 Feb 8. PUBMED ID: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30745171\">30745171<\/a><\/p>\n<p>Gatineau et al. <strong>Losartan prevents the elevation of blood pressure in adipose-PRR deficient female mice while elevated circulating sPRR activates the renin-angiotensin system.<\/strong> Am J Physiol Heart Circ Physiol. 2019 Mar 1;316(3):H506-H515. doi: 10.1152\/ajpheart.00473.2018. Epub 2018 Dec 14. PUBMED ID: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30550352\">30550352 <\/a><\/p>\n<p>Blass et al. <strong>Postprandial Effects on ENaC-Mediated Sodium Absorption.<\/strong> Sci Rep. 2019 Mar 12;9(1):4296. doi: 10.1038\/s41598-019-40639-x. PUBMED ID: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30862903\">30862903 <\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"5\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2615\" aria-expanded=\"false\">2018<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-2615\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"5\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-2615\" tabindex=\"0\" hidden=\"hidden\"><div class=\"toggle accent-color\" data-inner-wrap=\"true\">\n<h3><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Sharp et al. <\/span><strong style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">Renal Denervation Prevents Heart Failure Progression Via Inhibition of the Renin-Angiotensin System<\/strong><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">. J Am Coll Cardiol. 2018 Nov 27;72(21):2609-2621. doi: 10.1016\/j.jacc.2018.08.2186. PUBMED ID: <\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30466519\" style=\"font-size: 14px; font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">30466519<\/a><br><\/h3><div><div class=\"inner-toggle-wrap\"><div class=\"wpb_text_column wpb_content_element\"><div class=\"wpb_wrapper\">\n<p>Simko et al. <strong>Effect of Ivabradine on a Hypertensive Heart and the Renin-Angiotensin-Aldosterone System in L-NAME-Induced Hypertension<\/strong>. <span class=\"jrnl\" title=\"International journal of molecular sciences\">Int J Mol Sci<\/span>. 2018 Oct 3;19(10). pii: E3017. doi: 10.3390\/ijms19103017. 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PUBMED ID: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29500223\">29500223<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"6\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2616\" aria-expanded=\"false\">2017<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-2616\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"6\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-2616\" tabindex=\"0\" hidden=\"hidden\"><div class=\"toggle accent-color\" data-inner-wrap=\"true\">\n<h3><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Stowasser et al. <\/span><strong style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">Can Screening and Confirmatory Testing in the Management of Patients with Primary Aldosteronism be Improved? <\/strong><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Horm Metab Res. 2017 Dec;49(12):915-921. doi: 10.1055\/s-0043-121468. 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Published online 2016 Sep 09.<br>DOI: <a href=\"http:\/\/dx.doi.org\/10.1016\/j.healun.2016.08.022\">j.healun.2016.08.022.<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"8\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2618\" aria-expanded=\"false\">2015<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-2618\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"8\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-2618\" tabindex=\"0\" hidden=\"hidden\"><div class=\"toggle accent-color\" data-inner-wrap=\"true\">\n<h3><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Sabharwal R et al. <\/span><strong style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">Angiotensin-dependent autonomic dysregulation precedes dilated cardiomyopathy in a mouse model of muscular dystrophy.<\/strong><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\"> Exp Physiol. 2015 Jul 1;100(7):776-95.<\/span><br><\/h3><div><div class=\"inner-toggle-wrap\"><div class=\"wpb_text_column wpb_content_element\"><div class=\"wpb_wrapper\"><p>DOI: 10.1113\/EP085066. PUBMED ID: <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25921929\">25921929<\/a><\/p>\n<p>Roksnoer LC et al. <strong>Optimum AT1 receptor-neprilysin inhibition has superior cardioprotective effects compared with AT1 receptor blockade alone in hypertensive rats.<\/strong> Kidney Int. 2015 Jul;88(1):109-20.<br>DOI: 10.1038\/ki.2015.107. Epub 2015 Apr 1. PUBMED ID: <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25830765\">25830765<\/a><\/p>\n<p>Wysocki J et al. <strong>Plasma and Kidney Angiotensin Peptides: Importance of the Aminopeptidase A\/Angiotensin III Axis. Am J Hypertens.<\/strong> 2015 Dec; 28(12):1418-26.<br>DOI: 10.1093\/ajh\/hpv054. Epub 2015 May 11. PUBMED ID: <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25968123\">25968123<\/a><\/p>\n<p>Sharp S et al. <strong>Pharmacodynamic effects of C-domain-specific ACE inhibitors on the renin-angiotensin system in myocardial infarcted rats.<\/strong> J Renin Angiotensin Aldosterone Syst. 2015 Mar 9.<br>pii: 1470320314568438. PUBMED ID: <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25757657\">25757657<\/a><\/p>\n<p>Kovarik JJ et al. <strong>Molecular regulation of the renin-angiotensin system in haemodialysis patients.<\/strong> Nephrol Dial Transplant. 2015 Jan;30(1):115-23.<br>DOI: 10.1093\/ndt\/gfu265; PUBMED ID: <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25107336\">25107336<\/a><\/p>\n<p>Andersen LB et al. <strong>Vitamin D depletion aggravates hypertension and target-organ damage.<\/strong> J Am Heart Assoc. 2015 Jan 28;4(2).<br>DOI: 10.1161\/JAHA.114.001417; PUBMED ID: <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25630909\">25630909<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"9\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-2619\" aria-expanded=\"false\">2014<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-2619\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"9\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-2619\" tabindex=\"0\" hidden=\"hidden\"><div class=\"toggle accent-color\" data-inner-wrap=\"true\">\n<h3><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Manzel A et al. <\/span><strong style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">Angiotensin IV is induced in experimental autoimmune encephalomyelitis but fails to influence the disease.<\/strong><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\"> J Neuroimmune Pharmacol. 2014 Sep;9(4):533-43.DOI: 10.1007\/s11481-014-9548-y; PUBMED ID: <\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24854706\" style=\"font-size: 14px; font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">24854706<\/a><br><\/h3><div><div class=\"inner-toggle-wrap\"><div class=\"wpb_text_column wpb_content_element\"><div class=\"wpb_wrapper\">\n<p>Burger D et al. <strong>Effects of a domain-selective ACE inhibitor in a mouse model of chronic angiotensin II-dependent hypertension.<\/strong> Clin Sci (Lond). 2014 Jul;127(1):57-63.<br>DOI: 10.1042\/CS20130808. PUBMED ID: <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24506807\">24506807<\/a><\/p>\n<p>Haber PK et al. <strong>Angiotensin-converting enzyme 2-independent action of presumed angiotensin-converting enzyme 2 activators: studies in vivo, ex vivo, and in vitro.<\/strong> Hypertension. 2014 Apr;63(4):774-82.<br>DOI: 10.1161\/HYPERTENSIONAHA.113.02856. Epub 2014 Jan 20. PUBMED ID: <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24446061\">24446061<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"10\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-26110\" aria-expanded=\"false\">2013<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-26110\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"10\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-26110\" tabindex=\"0\" hidden=\"hidden\"><div class=\"toggle accent-color\" data-inner-wrap=\"true\">\n<h3><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Haschke M et al. <\/span><strong style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">Pharmacokinetics and pharmacodynamics of recombinant human angiotensin-converting enzyme 2 in healthy human subjects.<\/strong><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\"> Clin Pharmacokinet. 2013 Sep;52(9):783-92.<\/span><br><\/h3><div><div class=\"inner-toggle-wrap\"><div class=\"wpb_text_column wpb_content_element\"><div class=\"wpb_wrapper\"><p>DOI: 10.1007\/s40262-013-0072-7; PUBMED ID: <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23681967\">23681967<\/a><\/p>\n<p>Nikolaou A et al. <strong>[3H]IVDE77, a novel radioligand with high affinity and selectivity for the insulin-regulated aminopeptidase.<\/strong> Eur J Pharmacol. 2013 Feb 28;702(1-3):93-102.<br>DOI: 10.1016\/j.ejphar.2013.01.026. Epub 2013 Jan 31. PUBMED ID: <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/23376157\">23376157<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"11\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-26111\" aria-expanded=\"false\">2012<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-26111\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"11\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-26111\" tabindex=\"0\" hidden=\"hidden\"><div class=\"toggle default\" data-inner-wrap=\"true\">\n<h3><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\">Poglitsch M et al. <\/span><strong style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif;\">Recombinant Expression and Characterization of Human and Murine ACE2: Species-Specific Activation of the Alternative Renin-Angiotensin-System.<\/strong><span style=\"font-size: 14px; color: var( --e-global-color-text ); font-family: var( --e-global-typography-text-font-family ), Sans-serif; font-weight: var( --e-global-typography-text-font-weight );\"> Int J Hypertens. 2012;2012:428950.<\/span><br><\/h3><div><div class=\"inner-toggle-wrap\"><div class=\"wpb_text_column wpb_content_element\"><div class=\"wpb_wrapper\"><p>DOI: 10.1155\/2012\/428950; PUBMED ID: <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22518284\">22518284<\/a><\/p>\n<p>Ye M et al. <strong>Murine recombinant angiotensin-converting enzyme 2: effect on angiotensin II-dependent hypertension and distinctive angiotensin-converting enzyme 2 inhibitor characteristics on rodent and human angiotensin-converting enzyme 2.<\/strong> Hypertension. 2012 Sep;60(3):730-40.<br>DOI: <a href=\"http:\/\/hyper.ahajournals.org\/content\/60\/3\/730.abstract\">10.1161\/HYPERTENSIONAHA.112.198622<\/a>; PUBMED ID: <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22777933\">22777933<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Publication More research using our technology for RAAS profiling 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2022 \u00a0Briand et at. Diet-Induced Obesity and NASH Impair Disease Recovery in SARS-CoV-2-Infected Golden Hamsters. Viruses. 2022 Sep 17;14(9):2067. PUBMED: 36146875Cruz-L\u00f3pez et al. Blood pressure-independent renoprotective effects of small interference RNA targeting liver angiotensinogen in [&hellip;]<\/p>","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"<style>\/*! elementor - v3.6.8 - 27-07-2022 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h2>Pr\u00e4zise Diagnose f\u00fcr den  <\/p>\noptimalen Therapieerfolg\n<h4>Information f\u00fcr \u00c4rzte & Spezialisten<\/h4><\/h2>\t\t\n\t\t\t<h3>Bluthochdruck als Hauptrisiko f\u00fcr kardiovaskul\u00e4re Erkrankungen<\/h3>\t\t\n\t\t<p>Unkontrollierter Bluthochdruck betrifft mehr als 50% der behandelten Hypertonie-Patienten. Die zugrundeliegenden Ursachen sind vielf\u00e4ltig. In der klinischen Praxis ist es schwierig, die Ursache f\u00fcr eine persistierende Hypertonie zu identifizieren. Bisher verf\u00fcgbare diagnostische Screening-Instrumente f\u00fcr m\u00f6gliche Ursachen der sekund\u00e4ren Hypertonie, wie z.B. Prim\u00e4rer Hyperaldosteronismus, werden von blutdrucksenkenden Medikamenten gest\u00f6rt. Dabei ist mehr als jeder 10. Bluthochdruck-Patient von Prim\u00e4ren Hyperaldosteronismus betroffen. Ein Absetzen der medikament\u00f6sen Therapie f\u00fcr viele Tage vor dem Screening w\u00e4re erforderlich. Aus R\u00fccksicht auf das Wohl des Patienten sehen daher viele Mediziner von einem Screening ab, was zu sehr niedrigen Screening-Raten f\u00fchrt. Allgemeinmediziner m\u00fcssen h\u00e4ufig den langwierigen Weg von \u201eVersuch und Irrtum\u201c gehen, um den Blutdruck ihrer Patienten effektiv einzustellen. Ohne die zugrunde liegenden Ursachen zu kennen, kann dies zu Frustration und fehlender Behandlungsadh\u00e4renz bei Patienten, zu unn\u00f6tigen Medikamentenverschreibungen und auch zu einem ungewollten Anstieg des kardiovaskul\u00e4ren Gesamtrisikos f\u00fchren.<\/p>\t\t\n\t\t\t<style>\/*! elementor - v3.6.8 - 27-07-2022 *\/\n.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=\".svg\"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"250\" height=\"300\" src=\"http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_hypertonie-250x300.png\" alt=\"\" loading=\"lazy\" srcset=\"http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_hypertonie-250x300.png 250w, http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_hypertonie.png 460w\" sizes=\"(max-width: 250px) 100vw, 250px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t<h3>Einzigartiges Hypertonieprofil zur Ursachenabkl\u00e4rung<\/h3>\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"1024\" height=\"257\" src=\"http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_RAAS_profil-1024x257.png\" alt=\"\" loading=\"lazy\" srcset=\"http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_RAAS_profil-1024x257.png 1024w, http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_RAAS_profil-300x75.png 300w, http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_RAAS_profil-768x193.png 768w, http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_RAAS_profil-18x5.png 18w, http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_RAAS_profil-1080x271.png 1080w, http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_RAAS_profil-1280x321.png 1280w, http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_RAAS_profil-980x246.png 980w, http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_RAAS_profil-480x121.png 480w, http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_RAAS_profil-600x151.png 600w, http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_RAAS_profil.png 1298w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t<p>RAAS Triple-A\u2122 ist eine weltweit einzigartige Laboranalyse mit Therapieempfehlung f\u00fcr personalisiertes Blutdruck-Management. Dieses innovative, diagnostisches Verfahren beruht auf den Erkenntnissen aus 10 Jahren intensiver Forschung sowie umfangreicher klinischer Evidenz.\u00a0<\/p><p>Der RAAS Triple-A\u2122 Test macht die datenbasierte Stratifizierung von Patienten mit unkontrolliertem Bluthochdruck m\u00f6glich. Grundlage ist die klinische Massenspektrometrie. Sie liefert besonders hohe Genauigkeit bei der absoluten Quantifizierung von Hormonen durch interne Standardisierung und zeigt hervorragende Vergleichbarkeit zwischen den Ergebnissen verschiedener Laboratorien.\u00a0<\/p><p>Die Bestimmung der RAAS Triple-A\u2122 Hormone und der abgeleiteten Biomarker liefert ein einzigartiges biochemisches Hypertonieprofil, welches Aufschluss \u00fcber die zu Grunde liegenden Ursachen der Hypertonie geben kann. Auf dieser Basis kann die richtige Therapieentscheidung f\u00fcr den richtigen Patienten zur richtigen Zeit getroffen werden.\u00a0<\/p>\t\t\n\t\t\t<h3>Warum ist RAAS Triple-A\u2122 einzigartig?<\/h3>\t\t\n\t\t<h4>einfach.<\/h4><p>Die Blutabnahme erfolgt in Form eines Serum-R\u00f6hrchens unter laufender Medikation. Der RAAS Triple-A\u2122 Test verf\u00fcgt \u00fcber eine robuste Pr\u00e4-Analytik, ist in die Standard Laborroutine eingebunden und liefert eine klare klinische Interpretation auf Basis mehrerer blutdruckrelevanter Biomarker.<\/p><h4>personalisiert.<\/h4>\n<p>Der &uuml;bermittelte Befund enth&auml;lt die Messwerte, die RAAS Triple-A&trade; Biomarker und eine gezielte Therapieempfehlung unter Ber&uuml;cksichtigung der laufenden Medikation. Dieser bildet die Grundlage f&uuml;r eine effiziente und personalisierte Therapie von Bluthochdruck.<\/p><h4>effektiv.<\/h4>\n<p>Die Analyse basiert auf einem patentierten Verfahren, wird auf einem hochsensitiven <br \/>Massenspektrometer durchgef&uuml;hrt und garantiert exakte Messergebnisse. Die Nutzung von Angiotensinen als klinische Biomarker in der Hypertonie ist eine Weltneuheit und wurde in internationalen klinischen Studien validiert.<\/p>\t\t\n\t\t\t<h3>RAAS: Das Renin-Angiotensin-Aldosteron-System<\/h3>\t\t\n\t\t<p>Das RAAS Triple-A\u2122 Hypertonieprofil basiert auf einer Serumprobe, bei der zeitgleich mehrere blutdruckregulierende Hormone mittels klinischer Massenspektrometrie gemessen werden. \u201eTriple-A\u201c steht dabei f\u00fcr die drei zentralen Blutdruck-Effektor-Hormone des Renin-Angiotensin-Aldosteron-Systems. <br \/>Die Messwerte werden dann zur Berechnung der bahnbrechenden RAAS Triple-A\u2122 Biomarker verwendet.<\/p>\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"947\" height=\"539\" src=\"http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_aufbauRAAS.png\" alt=\"\" loading=\"lazy\" srcset=\"http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_aufbauRAAS.png 947w, http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_aufbauRAAS-300x171.png 300w, http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_aufbauRAAS-768x437.png 768w, http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_aufbauRAAS-480x273.png 480w, http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_aufbauRAAS-600x341.png 600w\" sizes=\"(max-width: 947px) 100vw, 947px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t<h3>Kombinierte Angiotensin-Biomarker<\/h3>\t\t\n\t\t<p>Die RAAS Triple-A\u2122 Biomarker setzen sich aus drei kombinierten Angiotensin-Biomarkern zusammen: PRA-S, dem Marker f\u00fcr Renin, ACE-S, dem Marker f\u00fcr die ACE-Aktivit\u00e4t und AA2-Ratio, dem Verh\u00e4ltnis von Aldosteron zu Angiotensin II.\u00a0<\/p><p>Neben einem Screening auf sekund\u00e4re Ursachen der Hypertonieerfassen die innovativen RAAS Triple-A\u2122 Biomarker auch die pharmakologische Wirksamkeit von RAAS-Blockern und damit auch Dosierung und Therapieadh\u00e4renz. Interpretation und Behandlungsempfehlungen basieren auf internationalen klinischen Validierungsstudien und sind im Einklang mit den geltenden Richtlinien der Fachgesellschaften.<\/p>\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"400\" height=\"284\" src=\"http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_photo1short-400x284.png\" alt=\"\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"227\" height=\"152\" src=\"http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_PRA_S.png\" alt=\"\" loading=\"lazy\" srcset=\"http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_PRA_S.png 227w, http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_PRA_S-18x12.png 18w\" sizes=\"(max-width: 227px) 100vw, 227px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"227\" height=\"152\" src=\"http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_ACES.png\" alt=\"\" loading=\"lazy\" srcset=\"http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_ACES.png 227w, http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_ACES-18x12.png 18w\" sizes=\"(max-width: 227px) 100vw, 227px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img width=\"227\" height=\"152\" src=\"http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_AA2.png\" alt=\"\" loading=\"lazy\" srcset=\"http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_AA2.png 227w, http:\/\/raastriple-a.com\/wp-content\/uploads\/2022\/07\/D_img_AA2-18x12.png 18w\" sizes=\"(max-width: 227px) 100vw, 227px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t<p>- Screening auf h\u00e4modynamisch wirksame renale Perfusionsst\u00f6rungen der Niere<br \/>- Beurteilung der pharmako-logischen Wirksamkeit<br \/>von RAAS-Blockern<\/p><p>- Beurteilung der pharmakologischen Wirksamkeit von ACE-Hemmern<br \/>- Bestimmungn der ACE-Aktivit\u00e4t<\/p><p>- Screening auf prim\u00e4ren \u00a0Hyperaldosteronismus (PHA)<\/p><p>- Beurteilung der pharmakologischen \u00a0 \u00a0Wirksamkeit von Sartanen<\/p>\t\t\n\t\t\t<h3>Erstellung eines Hypertonieprofils<\/h3>\t\t\n\t\t<p>Die RAAS Triple-A&trade;Analyse eignet sich besonders f&uuml;r Hypertoniker, die bisher nicht auf die Therapie ansprechen.<\/p>\n<p>Das Diagnoseverfahren erfordert die Gewinnung einer Serumprobe von mindestens 0,5 ml. Die Patienten sollten unter ihrer laufenden anti-hypertensiven Therapie getestet werden. Mit einer Stabilit&auml;t von mindestens acht Stunden bei Raumtemperatur ist die Pr&auml;-Analytik au&szlig;erordentlich robust und mit den g&auml;ngigen Laborabl&auml;ufen kompatibel.<\/p>\n<p>Der &uuml;bermittelte Befund enth&auml;lt die Messwerte, die RAAS Triple-A&trade; Biomarker und eine personalisierte Behandlungsempfehlung f&uuml;r den optimalen Therapieerfolg.<\/p>\n<p>Gemeinsam f&uuml;r eine bessere Lebensqualit&auml;t<\/p><h1>FAQ<\/h1><h1>Antworten auf h\u00e4ufige Fragen<\/h1><h2>____________<\/h2><h2>Allgemein<\/h2>\t\t\n\t\t\t<style>\/*! elementor - v3.6.8 - 27-07-2022 *\/\n.elementor-accordion{text-align:left}.elementor-accordion .elementor-accordion-item{border:1px solid #d4d4d4}.elementor-accordion .elementor-accordion-item+.elementor-accordion-item{border-top:none}.elementor-accordion .elementor-tab-title{margin:0;padding:15px 20px;font-weight:700;line-height:1;cursor:pointer;outline:none}.elementor-accordion .elementor-tab-title .elementor-accordion-icon{display:inline-block;width:1.5em}.elementor-accordion .elementor-tab-title .elementor-accordion-icon svg{width:1em;height:1em}.elementor-accordion .elementor-tab-title .elementor-accordion-icon.elementor-accordion-icon-right{float:right;text-align:right}.elementor-accordion .elementor-tab-title .elementor-accordion-icon.elementor-accordion-icon-left{float:left;text-align:left}.elementor-accordion .elementor-tab-title .elementor-accordion-icon .elementor-accordion-icon-closed{display:block}.elementor-accordion .elementor-tab-title .elementor-accordion-icon .elementor-accordion-icon-opened,.elementor-accordion .elementor-tab-title.elementor-active .elementor-accordion-icon-closed{display:none}.elementor-accordion .elementor-tab-title.elementor-active .elementor-accordion-icon-opened{display:block}.elementor-accordion .elementor-tab-content{display:none;padding:15px 20px;border-top:1px solid #d4d4d4}@media (max-width:767px){.elementor-accordion .elementor-tab-title{padding:12px 15px}.elementor-accordion .elementor-tab-title .elementor-accordion-icon{width:1.2em}.elementor-accordion .elementor-tab-content{padding:7px 15px}}<\/style>\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"\">Welche Patienten profitieren von der Untersuchung?<\/a>\n\t\t\t\t\tLorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.\n\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"\">Was ist bei der Untersuchung zu beachten?<\/a>\n\t\t\t\t\tLorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.\n\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"\">Was wird beim  RAAS Triple-A\u2122 Test gemessen?<\/a>\n\t\t\t\t\tLorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.\n\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"\">Wozu dienen die RAAS Triple-A\u2122 Biomarker?<\/a>\n\t\t\t\t\tLorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.\n\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"\">Wie entsteht ein  RAAS Triple-A\u2122 Befund?<\/a>\n\t\t\t\t\tLorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.\n\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"\">Welche Informationen liefert der Befund?<\/a>\n\t\t\t\t\t<p>Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.<\/p>\n\t\t<h2>____________<\/h2><h2>Logistik<\/h2>\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"\">Wie funktioniert die Probenlogistik?<\/a>\n\t\t\t\t\tLorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.\n\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"\">Wie lange k\u00f6nnen die Proben gelagert werden?<\/a>\n\t\t\t\t\tLorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.\n\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"\">Wie lange dauert es, bis ich das Testergebnis bekomme?<\/a>\n\t\t\t\t\tLorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.\n\t\t\t<h3>Sie sind an der RAAS Triple-A\u2122 Analyse interessiert?<br><br>Kontaktieren Sie uns <br><br>\nDownload Portal<\/h3>\t\t\n\t\t\t<style>\/*! elementor - v3.6.8 - 27-07-2022 *\/\n.e-container.e-container--row .elementor-spacer-inner{width:var(--spacer-size)}.e-container.e-container--column .elementor-spacer-inner,.elementor-column .elementor-spacer-inner{height:var(--spacer-size)}<\/style>\t\t\n\t\t<h1>Zum Newsletter anmelden<\/h1>","_et_gb_content_width":"","footnotes":""},"class_list":["post-3280","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/raastriple-a.com\/de\/wp-json\/wp\/v2\/pages\/3280","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/raastriple-a.com\/de\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/raastriple-a.com\/de\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/raastriple-a.com\/de\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/raastriple-a.com\/de\/wp-json\/wp\/v2\/comments?post=3280"}],"version-history":[{"count":40,"href":"https:\/\/raastriple-a.com\/de\/wp-json\/wp\/v2\/pages\/3280\/revisions"}],"predecessor-version":[{"id":3378,"href":"https:\/\/raastriple-a.com\/de\/wp-json\/wp\/v2\/pages\/3280\/revisions\/3378"}],"wp:attachment":[{"href":"https:\/\/raastriple-a.com\/de\/wp-json\/wp\/v2\/media?parent=3280"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}